Common questions
What is the Advanced Recomp Stack?
The Advanced Recomp Stack combines retatrutide, CJC-1295 (No DAC), and ipamorelin in a 3-compound body recomposition protocol. Retatrutide drives fat loss. CJC-1295 + ipamorelin boost growth hormone to support lean tissue during the deficit. No published human trial has tested all three together.
Can you stack retatrutide with CJC-1295 and ipamorelin together?
Yes. Retatrutide and CJC-1295 + ipamorelin work through completely different receptor systems. Retatrutide hits metabolic receptors (GLP-1, GIP, glucagon). CJC and ipamorelin hit growth-hormone receptors (GHRH-R, GHS-R1a). There is no receptor overlap. The combination is community-derived, not from a clinical trial.
How is the Advanced Recomp Stack dosed?
Retatrutide is dosed once a week via subQ injection, titrated from 2 mg up to 9-12 mg over 16-20 weeks. CJC-1295 (No DAC) and ipamorelin are each dosed at 100-200 mcg per shot, 1-2 times daily, with the main shot before bed in a fasted state.
Should I use a pre-blended CJC + ipamorelin vial or separate vials?
Most users pick the pre-blended CJC/Ipa combo vial because it cuts reconstitution from three vials to two and locks in a 1:1 ratio. Separate vials are better if you need to run one peptide higher than the other. Retatrutide always stays as its own separate vial.
How do you reconstitute the Advanced Recomp Stack?
Each compound is reconstituted on its own. Common setups: retatrutide 10 mg + 2 mL BAC water = 5 mg/mL; CJC-1295 2 mg + 1 mL BAC water = 2,000 mcg/mL; ipamorelin 5 mg + 2.5 mL BAC water = 2,000 mcg/mL. For a pre-blended CJC + ipa combo vial (5 mg + 5 mg) reconstituted with 2 mL BAC water, you get 2,500 mcg/mL of each peptide.
Open the reconstitution calculator →Why use CJC-1295 without DAC instead of the with-DAC version?
CJC-1295 No DAC produces short GH pulses — your levels spike, then come back down, which matches the body's natural rhythm. The with-DAC version keeps GH elevated for days. This stack is built around natural-style pulses, so the No DAC version is the intended fit. No DAC is also easier to adjust if you need to change your dose.
How long should you run the Advanced Recomp Stack?
Standard cycles run 12-16 weeks. Extended cycles run 16-24 weeks. CJC-1295 + ipamorelin are usually cycled 12 weeks on and 4 weeks off to reduce receptor desensitization. Retatrutide can continue through the CJC/Ipa off-period when ongoing weight-management support is needed.
Is the Advanced Recomp Stack safe? What are the main risks?
No clinical trial has tested all three together. The biggest known risks are retatrutide-driven GI side effects (nausea 38-43%, diarrhea 33-35%) and dysesthesia — an unusual skin tingling or burning sensation at higher doses. Adding CJC/Ipa brings injection-site reactions and mild water retention. People with pre-diabetes or insulin resistance should monitor blood glucose more often because retatrutide and GH push insulin sensitivity in opposite directions.