Ipamorelin is a research peptide that signals the pituitary to release the body's own growth hormone in natural pulses.

What is the starting dose of ipamorelin?

The common starting dose is 100 mcg per shot, once daily at bedtime, on an empty stomach.

What is the ipamorelin dosage chart by vial size?

For a 10 mg vial with 3.0 mL BAC water: 200 mcg = 6 units.

How is ipamorelin reconstituted?

Common setups are 1.0 mL BAC water for a 2 mg vial, 2.0 mL BAC water for a 5 mg vial, and 3.0 mL BAC water for a 10 mg vial.

What is ipamorelin's half-life?

Ipamorelin has a terminal plasma half-life of about 2 hours.

Is ipamorelin FDA-approved?

No, ipamorelin is not FDA-approved for any human use.

What is the ipamorelin dosage for women?

Research-community protocols often use 100-200 mcg per shot for women.

What is the ipamorelin dosing schedule for beginners?

A common beginner schedule is 100 mcg per shot, one shot per day at bedtime, for one week.

Hormone-relatedsubcutaneous

Ipamorelin

Ipamorelin is a selective growth-hormone secretagogue studied in pituitary research models.

Researched for

SleepBody CompositionRecoveryPerformance RecoveryLongevity

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You will almost never hear ipamorelin mentioned without CJC-1295, and there is a real reason researchers pair them.

Not yet audited

We have not published an audit on Ipamorelin. Everything below is reference material, not our own reading of the literature, treat it as a starting point for questions, not as a grade.

How it is thought to work

Ghrelin-receptor agonist; GH release signaling.

Ipamorelin tells the pituitary gland to release a short, natural pulse of growth hormone by binding to the GHS-R1a (ghrelin) receptor, without raising stress hormones like cortisol or prolactin the way similar peptides do.

Reported side effects

What sources report

Reference, not a recommendation

These are figures published elsewhere, reproduced with their source. Peppersite does not recommend an amount for Ipamorelin or for anything else, and nothing below has been checked against the study it came from.

Amount	Frequency	Route	Reported by
200-300 mcg per injection	not stated8-12 weeks, then 2-4 weeks off · Repeatable	subcutaneous	Peptide Protocol Wiki What it saysHide (secondary reference; provider confirmation required).
Standard: 200-300 mcg/day · Low: 100 mcg/day · High: 300 mcg	1-3 times per day8-12 weeks on, then 4 weeks off · 8-12 weeks	subcutaneous	Peptide Dosing Protocols What it saysHide (secondary reference; provider confirmation required). Half-life: about two hours. Most research protocols use 100 to 300 mcg per shot, one to three times per day.
Referenced at 100-300 mcg (0.1-0.3 mg) per dose. Commonly paired with CJC-1295 for synergistic GH release with minimal cortisol or prolactin elevation. Sample stacks cite 100 mcg each, fasted morning and before bed.	2-3x daily (vitality contexts cite once daily) · Morning fasted, pre-workout, or before bedOn-cycle 8-12 weeks, off-cycle 4 weeks	subcutaneous	Peptide Therapy Reference Text, internal KB v4 What it saysHide (Aug 2026), secondary reference; provider confirmation required.

200-300 mcg per injection

Frequency: not stated8-12 weeks, then 2-4 weeks off · Repeatable
Route: subcutaneous
Reported by: Peptide Protocol Wiki
What it saysHide
(secondary reference; provider confirmation required).

Standard: 200-300 mcg/day · Low: 100 mcg/day · High: 300 mcg

Frequency: 1-3 times per day8-12 weeks on, then 4 weeks off · 8-12 weeks
Route: subcutaneous
Reported by: Peptide Dosing Protocols
What it saysHide
(secondary reference; provider confirmation required). Half-life: about two hours. Most research protocols use 100 to 300 mcg per shot, one to three times per day.

Referenced at 100-300 mcg (0.1-0.3 mg) per dose. Commonly paired with CJC-1295 for synergistic GH release with minimal cortisol or prolactin elevation. Sample stacks cite 100 mcg each, fasted morning and before bed.

Reconstitution, as reported

Bacteriostatic water
3.0 mL BAC water for 10 mg vial

Ipamorelin

How it is thought to work

Reported side effects

Who should avoid it

What gets monitored